Antibiotic Potency Test
BACKGROUND:
Eurofins | ams is able to perform antibiotic potency testing by the bioassay method. Antibiotic potency is estimated by comparing the inhibition of growth of sensitive micro-organisms produced by known concentrations of the antibiotic being examined against a reference standard substance. The test is performed on raw materials and finished products to confirm the antibiotic activity meets specifications.
PRINCIPLE OF TEST:
All test methods are based on the European and British Pharmacopeia: Biological assay of antibiotics, BP Appendix XIV A (Ph. Eur. method 2.7.2)
This is a large-plate format procedure where test and standard preparations are loaded into wells in a randomized latin square arrangement before incubation and reading the zones of inhibition.
List of Antimicrobials available are as shown below.
| Amphotericin B |
| Bacitracin |
| Bleomycin |
| Colistin |
| Colistimethate |
| Dihydrostreptomycin |
| Erythromycin |
| Framycetin |
| Gentamicin |
| Kanamycin |
| Neomycin |
| Netilmicin |
| Nystatin |
| Polymyxin B |
| Rifamycin |
| Spiramycin |
| Streptomycin |
| Tobramycin |
| Tylosin |
| Vancomycin |
We can also perform Antimicrobial Activity Tests such as those shown below.
| Minimum Inhibition Concentration (MIC) Test |
| Minimum Bactericidal Concentration (MBC) Test |
| Minimum Kill Concentration ( MKC) Test |
| Zone of Inhibition (ZOI) Test |
